Washing Without a Sink

SINK SINK SOURCE SINK SINK Channel Process C Process

The Internet and the Grid are changing the face of high performance computing. Rather than tightly-coupled SPMD-style components running in a single cluster, on a parallel machine, or even on the Internet programmed in MPI, applications are evolving into sets of cooperating components scattered across diverse computational elements. These components may run on diierent operating systems and har...

How does washing without water perform compared to the traditional bed bath: a systematic review

BACKGROUND For immobile patients, a body wash in bed is sometimes the only bathing option. Traditionally, the bed bath is performed with water and soap. However, alternatives are increasingly used in health care. Washing without water is one such alternative that has been claimed to offer several advantages, such as improved hygiene and skin condition. This systematic review aims to provide a c...

Autophagy plays a WASHing game.

Beclin 1 is a crucial regulator of autophagy. It forms a complex with ATG14L, VPS34 or the class III phosphatidylinositol 3-kinase AMBRA1 to control autophagosome formation. A study in this issue of The EMBO Journal (Xia et al, 2013) reports that WASH, a protein known to regulate endosomal sorting, hampers autophagy by inhibiting the AMBRA1-dependent polyubiquitylation of Beclin 1. This modific...

Green Washing

Fracture as a material sink

Cracks are created by massive breakage of molecular or atomic bonds. The latter, in its turn, leads to the highly localized loss of material, which is the reason why even closed cracks are visible by a naked eye. Thus, fracture can be interpreted as the local material sink. Mass conservation is violated locally in the area of material failure. We consider a theoretical formulation of the couple...